Drug Discov Ther. 2017;11(5):288-290. (DOI: 10.5582/ddt.2017.01051)

Evaluation of the innate immune-stimulating activity of amazake using a silkworm muscle contraction assay.

Maruki-Uchida H, Sai M, Sekimizu K

We evaluated the innate immune-stimulating activity of amazake using a silkworm muscle contraction assay. Sake cake, a raw material used to make amazake, had high innate immunity-stimulating activity, whereas rice malt, another raw material used to make amazake, did not, even after fermentation. These results suggest that the silkworm muscle contraction assay is a useful tool to screen foods with high innate immune-stimulating activity and that amazake made from sake cake has immunomodulatory potential.

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