Drug Discov Ther. 2018;12(4):239-247. (DOI: 10.5582/ddt.2018.01039)

Whole body vibration exercise in the management of cancer therapy-related morbidities: A systematic review.

Lopes-Souza P, Dionello CF, Sá-Caputo DC, Moreira-Marconi E, Frederico EHFF, Marchon RM, Bergmann A, Furness T, Bernardo-Filho M


The purpose of this systematic review was to investigate the effects of whole body vibration (WBV) exercise in the management of cancer therapy-related morbidities. The PubMED and PEDro databases were used to access publications published in English about the use of whole body vibration (WBV) exercises in cancer patients until February 22nd 2017. The studies included were classified according to the level of evidence (LE) by the National Health and Medical Research Council Hierarchy of evidence and the methodological quality (MQ) by the PEDro scale. The four included studies (2 of them with "high" LE-II and MQ) were performed in patients with different types of cancer (i.e. breast, lung, prostate, solid or hematological), treated with WBV exercise to counteract the cancer therapy-related morbidities. The variables evaluated were muscle activity, subjective rate of perceived exertion, exercise capacity, muscle strength, quality of life, resting urinary incontinence and severity of peripheral neuropathy. Although WBV exercise appears to be a potential treatment procedure of cancer therapy-related morbidities, further additional studies are required to determine specific and tailored protocols to be used in the different stages of the disease.

KEYWORDS: Whole body vibration, cancer, oncology, rehabilitation, exercise

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