Drug Discov Ther. 2019;13(3):175-176. (DOI: 10.5582/ddt.2019.01042)

Brain abscess in an angiosarcoma patient during a disease-free interval.

Kuriyama H, Kajihara I, Kanemaru H, Nishimura N, Igata T, Masuguchi S, Imaoka Y, Makino K, Ihn H

This is the first case of an angiosarcoma patient with brain abscess, and it might be responsible for skin defect and cranial bone necrosis by surgical excision and radiation. Our patient was treated with 10 courses of triweekly paclitaxel therapy, radical radiotherapy (70 Gy), and surgical excision (2 cm margin apart from a lesion) for angiosarcoma. At two years after the operation he was diagnosed as brain abscess. Brain abscess was managed with antibiotic drugs and drainage, his clinical symptoms improved by these treatments. He achieves replace free survival without the exacerbation of angiosarcoma and brain abscess for three years.

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