Drug Discov Ther. 2020;14(2):73-76. (DOI: 10.5582/ddt.2020.01015)
Rapid review for the anti-coronavirus effect of remdesivir
Li ZY, Wang XJ, Cao DL, Sun RL, Li C, Li GW
The outbreak of SARS-CoV-2 rapidly spread across China and worldwide. Remdesivir had been proposed as a promising option for treating coronavirus disease 2019 (COVID-19). We provided a rapid review to critically assess the potential anti-coronavirus effect of remdesivir on COVID-19 and other coronaviruses based on the most up-to-date evidence. Even though remdesivir was proposed as a promising option for treating COVID-19 based on laboratory experiments and reports from compassionate use, its safety and effect in humans requires high-quality evidence from welldesigned and adequately-powered clinical trials for further clarification.