Drug Discov Ther. 2022;16(2):96-98. (DOI: 10.5582/ddt.2022.01024)

Linezolid for patients with multidrug-resistant tuberculosis/ extensively drug-resistant tuberculosis in China

Zhang PZ, Tan J, Lin Y, Zhang HL, Deng GF, Chen XY


Linezolid has been one of the key anti-tuberculosis agents for the treatment of multidrug-resistant tuberculosis (MDR-TB)/extensively drug-resistant tuberculosis (XDR-TB). It used to be very expensive and was not covered by social insurance from local governments. Nevertheless, a growing number of patients in China received linezolid in their anti- MDR/XDR TB regimens over the past decade. Many scholars in China have reported their experience using linezolid to treat patients with MDR/XDR-TB. In view of this, existing evidence of the efficacy and safety of linezolid and problems faced by Chinese patients with MDR/XDR-TB are summarized here.

KEYWORDS: Linezolid, MDR/XDR-TB, China, drug resistance

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