Drug Discov Ther. 2013;7(1):24-28. (DOI: 10.5582/ddt.2013.v7.1.24)
New phenolic compounds from the twigs of Artocarpus heterophyllus.
Di XX, Wang SQ, Wang B, Liu YQ, Yuan HQ, Lou HX, Wang XN
SUMMARY
Two new chalcones, artocarpusins A and B (1 and 2), one new flavone, artocarpusin C (3), one new 2-arylbenzofuran derivative, artocarstilene A (4), and 15 flavonoids were isolated from the twigs of Artocarpus heterophyllus. Their structures were established on the basis of extensive spectroscopic analysis. Compounds 9 and 16 showed moderate inhibitory activity on the proliferation of the PC-3 and H460 cell lines.
KEYWORDS: Artocarpus heterophyllus, chalcone, flavone, 2-arylbenzofuran, cytotoxicity
Full Text: 
