The conversion window in hepatocellular carcinoma: When resectability alone is not an indication for surgery

Zhu WP, Wang L, Tang W

Drug Discov Ther. 2026; 20(5):360-364.

DOI: 10.5582/ddt.2026.01068

Clinical investigation of effects of eldecalcitol on lipid profile and other metabolic parameters in osteoporosis-treatment-naïve postmenopausal women with osteoporosis

Abe I, Ochi K, Fujita Y, Kubo K, Wada T, Hirakawa I, Sakata H, Takeshita K, Nagata M, Tokieda M, Mitsuoka R, Yamashita Y, Higashi A, Kato T, Kudo T, Takashi Y, Abe M, Mukoubara S, Kobayashi K

Drug Discov Ther. 2026; 20(5):365-369.

DOI: 10.5582/ddt.2026.01057

HSD17B12 deficiency is associated with granulosa cell apoptosis and inflammatory transcriptomic signatures in experimental premature ovarian insufficiency models

Yuan XX, Zhao HJ, Yan HL, Yang G, Wang Y

Drug Discov Ther. 2026; 20(5):370-380.

DOI: 10.5582/ddt.2026.01013

Hot-water extraction, ethanol precipitation, and silkworm bioassays detect innate immune-stimulating activity in coffee extracts

Miyashita A, Mikami K, Tabuchi F, Sekimizu K

Drug Discov Ther. 2026; 20(5):381-384.

DOI: 10.5582/ddt.2026.01061

Collagen-derived peptides enhance resistance to Pseudomonas aeruginosa infection in silkworms

Miyashita A, Tabuchi F, Mikami K, Nakajima H, Kuwaba K, Mizuno K, Taga Y, Kusubata M, Sekimizu K

Drug Discov Ther. 2026; 20(5):385-390.

DOI: 10.5582/ddt.2026.01062

Patients' perceptions of hypnotic medications and factors associated with the desire to discontinue among regular users: A cross-sectional questionnaire survey in community pharmacies

Ishimura A, Ichikawa D, Watanabe T, Shimizu Y, Yabuki N

Drug Discov Ther. 2026; 20(5):391-396.

DOI: 10.5582/ddt.2026.01065

Bepirovirsen: The first antisense oligonucleotide approved to achieve a functional cure for chronic hepatitis B

Sun YY, Gao JJ

Drug Discov Ther. 2026; 20(5):397-399.

DOI: 10.5582/ddt.2026.01064

Daraxonrasib: The first-in-class RAS(ON) multi-selective inhibitor approved for treatment of metastatic pancreatic adenocarcinoma

Sun YY, Pang C, Gao JJ

Drug Discov Ther. 2026; 20(5):400-402.

DOI: 10.5582/ddt.2026.01067

Rebisufligene etisparvovec: The first AAV9-mediated SGSH gene therapy approved for the treatment of mucopolysaccharidosis type IIIA (MPS IIIA)

Pang C, Sun YY, Gao JJ

Drug Discov Ther. 2026; 20(5):403-404.

DOI: 10.5582/ddt.2026.01082

Surgical indications for hepatocellular adenoma: Diagnostic uncertainty and molecular risk stratification

Tan JY, Shen A

Drug Discov Ther. 2026; 20(5):405-408.

DOI: 10.5582/ddt.2026.01086