Drug Discov Ther. 2024;18(5):269-276. (DOI: 10.5582/ddt.2024.01063)

Novel and emerging therapeutics for antimicrobial resistance: A brief review

Kuchay RAH


SUMMARY

A pandemic known as anti-microbial resistance (AMR) poses a challenge to contemporary medicine. To stop AMR's rise and quick worldwide spread, urgent multisectoral intervention is needed. This review will provide insight on new and developing treatment approaches for AMR. Future therapy options may be made possible by the development of novel drugs that make use of developments in "omics" technology, artificial intelligence, and machine learning. Vaccines, immunoconjugates, antimicrobial peptides, monoclonal antibodies, and nanoparticles may also be intriguing options for treating AMR in the future. Combination therapy may potentially prove to be a successful strategy for combating AMR. To lessen the impact of AMR, ideas like drug repurposing, antibiotic stewardship, and the one health approach may be helpful.


KEYWORDS: anti-microbial resistance, mechanisms, drugs, therapeutics, FDA approved, monoclonal antibodies, anti-microbial peptides, AMR vaccines

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